What is the maximum recommended time to take the second dose of Bupropion?

The maximum recommended time to take the second dose of Bupropion is typically advised to be no later than 5 PM. This recommendation is primarily based on the pharmacological properties of Bupropion, which is a stimulant-type antidepressant that can potentially interfere with sleep if taken too late in the day.

Taking the second dose later in the evening, especially after 5 PM, may lead to increased energy levels or insomnia, potentially impacting the patient's ability to fall asleep. It is crucial to maintain an adequate spacing of doses to ensure therapeutic effectiveness while minimizing side effects. This is why the guidance often emphasizes timing the second dose in the early afternoon to early evening.